BIOVIA Discovery Studio’s Unmatched Capabilities in Biologics & Antibody Engineering
Discovery Studio Simulation is the market-leading modeling suite for biotherapeutics that offer complete in silico workflows with best-in-class computational methods and generative AI (GenAI), supporting researchers from structure prediction to epitope mapping, affinity maturation, humanization, solubility prediction, and excipient formulation.
With Discovery Studio Simulation, researchers focus on candidates most likely to succeed in the clinic, accelerate timelines, reduce costs, and streamline the traditionally labor-intensive process of biotherapeutics discovery.
- Predictions & 3D Modeling: Generate high-quality 3D models of target proteins with OpenFold/AlphaFold AI models or with MODELER, the market-leading homology modeling algorithm.
- Molecular Dynamics Simulations: Simulate protein dynamics with CHARMm, NAMD, OpenMM to refine 3D structures and gain insight into mechanisms of action. Gaussian-accelerated MD explores conformational space.
- Developability Assessment: Predict aggregation (SAP), solubility, and viscosity early in the pipeline to de-risk downstream development.
- Humanization: Utilize advanced machine learning protocols to humanize antibody sequences, reducing immunogenicity while preserving binding affinity.
- De novo Binder Design: Discover novel protein binders to your target protein with GenAI.
